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Updated: Oct 4, 2026

An In Vitro Enzymatic Assay to Measure Transcription Inhibition by Gallium(III) and H3 5,10,15-tris(pentafluorophenyl)corroles
Published on: March 18, 2015
[Gallic acid: a potent inhibitor of tetramethylbenzidine peroxidation in aqueous and micellar media]
E I Karaseva1, T V Nikiforova, D I Metelitsa
1Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus, Minsk, Republic of Belarus 220141.
Abstract:
Gallic acid competitively inhibited 3,3',5,5'-tetramethylbenzidine peroxidation both in 0.01 M phosphate buffer (pH 6.4) (KI 13.3 microM) and in reversed aerosol OT micelles of different hydration degrees dispersed in heptane (KI 21.3 to 29.3 microM). The average number of free radical particles terminated by one inhibitor molecule (f) was estimated to be 1.3 to 1.6 in aqueous buffer solutions and 1.08 to 2.72 in reversed micelles, depending on their hydration.
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