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[Diagnostic image (32). Gout tophus].

J L Blaauwgeers1, W Hart

  • 1Onze Lieve Vrouwe Gasthuis, afd. Pathologie, Postbus 95.500, 1090 HM Amsterdam. j.l.g.blaauwgeers@olvg.nl

Nederlands Tijdschrift Voor Geneeskunde
|September 4, 2001
PubMed
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A man with gout developed a Pseudomonas infection in a tophus on his right first toe. This case highlights a rare complication of gout, emphasizing the need for vigilance in managing infected tophi.

Area of Science:

  • Rheumatology
  • Infectious Diseases
  • Podiatry

Background:

  • Gout is a common inflammatory arthritis characterized by hyperuricemia and urate crystal deposition.
  • Tophi are urate crystal aggregates that can form in soft tissues, often associated with chronic gout.
  • Secondary infections of tophi can occur, though they are relatively uncommon.

Observation:

  • A 65-year-old male patient presented with a history of gout.
  • The patient had a secondary infection of a tophus located at the first metatarsophalangeal joint of the right foot.
  • The causative pathogen identified was Pseudomonas.

Findings:

  • The case illustrates a rare instance of Pseudomonas infection complicating a gout tophus.
  • The infection localized to the metatarsophalangeal joint, a common site for gouty arthritis.

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  • Prompt identification and management of such infections are crucial for patient outcomes.

    • Implications:

    • This case underscores the importance of considering infectious etiologies in patients with gout, especially those with tophi.
    • Effective antibiotic therapy targeting Pseudomonas is essential for resolving infected tophi.
    • Further research into the risk factors and optimal management strategies for infected tophi may be warranted.