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Pemphigus in the southeastern United States
1Department of Dermatology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Southern Medical Journal
|September 4, 2001
Summary
Pemphigus affects diverse populations in the southeastern US, with delayed diagnosis impacting treatment outcomes. Complications from the disease and its therapy are significant, highlighting the need for prompt management.
Area of Science:
- Dermatology
- Autoimmune Diseases
- Clinical Medicine
Background:
- Pemphigus is a rare autoimmune blistering disease.
- Understanding its course and management is crucial for patient outcomes.
Purpose of the Study:
- To review the clinical course and management of pemphigus patients.
- To analyze treatment outcomes at a tertiary care center in the southeastern United States.
Main Methods:
- Retrospective review of 30 pemphigus patients.
- Data collected from January 1992 to July 1999 at Emory Clinic.
Main Results:
- Pemphigus affected diverse ethnic groups equally, with pemphigus vulgaris being more common.
- Delayed diagnosis averaged 4.5-6 months; 47% required hospitalization.
- 93% needed adjuvant therapy alongside systemic corticosteroids; 33% experienced herpes gingivostomatitis and 33% achieved remission.
Conclusions:
- Pemphigus presents across various ethnic groups in the southeastern US.
- Delayed diagnosis and prompt treatment are critical issues.
- Significant complications arise from both pemphigus and its treatment.