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Updated: Oct 4, 2026

High-Temperature and High-Pressure In situ Magic Angle Spinning Nuclear Magnetic Resonance Spectroscopy
Published on: October 9, 2020
Rotor synchronization of radiofrequency and gradient pulses in high-resolution magic angle spinning NMR
J M Wieruszeski1, G Montagne, G Chessari
1UMR 8525 CNRS, Institut de Biologie de Lille, Institut Pasteur de Lille, Université de Lille II, 1 rue du Professeur Calmette, 59021 Lille Cedex, France.
Abstract:
We have investigated the extent to which rotor synchronization of radiofrequency pulses leads to spectral improvement in high-resolution magic angle spinning NMR experiments. Several pulse sequences were tested, and the effect was found to be maximal in homonuclear TOCSY spectra. The physicochemical nature of the sample plays a role in the phenomenon, as rotor synchronization allows the refocusing of residual anisotropic interactions. However, even in a liquid sample the effects were visible. Radial inhomogeneities of the radiofrequency field were identified as an important source of the problem.
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