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Trabecular eccentricity and bone adaptation.

J C Fox1, T M Keaveny

  • 1Orthopaedic Biomechanics Laboratory, Department of Mechanical Engineering, 2166 Etcheverry Hall, University of California, Berkeley, CA 94720-1740, USA. jcfox@me.berkeley.edu

Journal of Theoretical Biology
|September 5, 2001
PubMed
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Bone adaptation involves more than density or orientation. Trabecular eccentricity, or non-central bone placement, protects the human femoral neck by altering stress distribution, revealing a new bone adaptation mechanism.

Area of Science:

  • Biomechanics
  • Orthopedics
  • Skeletal Biology

Background:

  • Bones adapt through density, geometry, and trabecular orientation.
  • Trabecular eccentricity, the non-central placement of trabecular bone within the cortical envelope, is proposed as another adaptation mechanism.

Purpose of the Study:

  • To demonstrate the biomechanical significance of trabecular eccentricity in the human femoral neck.
  • To provide a mechanistic explanation for the relationship between trabecular eccentricity and stress distribution.

Main Methods:

  • Utilized composite beam theory to analyze stress distribution.
  • Investigated the effects of varying degrees of trabecular eccentricity.

Main Results:

  • Trabecular eccentricity alters stress, increasing it superiorly and decreasing it inferiorly in the femoral neck.

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  • This asymmetric stress distribution provides a protective effect.

    • Conclusions:

    • Trabecular eccentricity is a significant bone adaptation mechanism.
    • Asymmetric placement of trabecular bone within the cortical envelope aids in adapting to mechanical demands.