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Prevalence and morbidity associated with non-malignant, life-threatening conditions in childhood
S Lenton1, P Stallard, M Lewis
1Department of Child Health, Bath and West Community NHS Trust, Bath, UK.
Insights
Non-malignant life-threatening illnesses in children are more common than previously thought, affecting 1.2 per 1000 children. These conditions cause significant child and family morbidity, requiring comprehensive support.
Area of Science:
- Pediatric Health
- Epidemiology
- Family Medicine
Background:
- Non-malignant life-threatening illnesses (NMLTIs) in children are a significant health concern.
- Previous estimates of NMLTI prevalence may be underestimated.
Purpose of the Study:
- To determine the prevalence of NMLTIs in childhood.
- To assess the associated morbidity in affected children and their family members.
Main Methods:
- A cross-sectional survey was conducted in the Bath Clinical Area.
- The study included children aged 0-19 years.
Main Results:
- A prevalence of 1.2/1000 children was identified, four times greater than previous estimates.
- Morbidity in affected children included pain (60%), inability to walk (35%), and severe cognitive impairment (25%).
- Family members experienced significant mental health issues (mothers 54%, fathers 30%) and siblings showed behavioral problems (24%).
Conclusions:
- NMLTIs are more prevalent than previously reported.
- These conditions impose considerable morbidity on both the child and their family.
- An integrated, family-centered approach with early assessment and intervention is crucial.
Objective:
To determine the prevalence of non-malignant life-threatening illness in childhood and associated morbidity in the affected child and their family members.
Design:
Cross-sectional survey.
Setting:
Bath Clinical Area (total population 411,800).
Subjects:
Children aged 0-19 years.
Results:
One hundred and twenty-three children were identified, giving a prevalence of 1.2/1000 children. Morbidity assessed in 93 children showed 60% in pain or discomfort, 35% unable to walk and 25% with severe cognitive impairment. Mental health problems were found in 54% of mothers and 30% of fathers, and significant emotional and behavioural problems in 24% of healthy siblings.
Conclusions:
Non-malignant life-threatening illness is more prevalent than reported in previous studies. Considerable morbidity is experienced by the child and their family. An individual and family approach is required. Key messages (1) The prevalence of non-malignant life-threatening illness is four times greater than previous estimates. (2) This group of conditions have significant implications for all family members. (3) Early comprehensive assessment and access to effective interventions may pre-empt later problems.
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