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Updated: Jul 16, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
Leukaemia presenting as respiratory distress in a child with asthma
1Department of Pediatric Hematology and Oncology, New York Presbyterian Hospital and Weill Medical College of Cornell University, New York, NY, USA. heathj@mskcc.org
Insights
Asthma is a common cause of pediatric emergency department visits for shortness of breath. While diagnosis is often straightforward, consider other conditions for atypical presentations.
Area of Science:
- Pediatric emergency medicine
- Respiratory diseases
Background:
- Asthma is the leading cause of emergency department visits for pediatric shortness of breath.
- Diagnosis typically involves atopy history, physical exam for reactive airways disease, and bronchodilator response.
Observation:
- Most asthma diagnoses in children are clinically straightforward.
- Atypical presentations or unexplained findings warrant consideration of differential diagnoses.
Findings:
- Standard diagnostic criteria for asthma are effective in most pediatric cases.
- Unusual presentations necessitate a broader diagnostic approach.
Implications:
- Clinicians should maintain a high index of suspicion for alternative diagnoses in pediatric respiratory distress.
- Accurate diagnosis is crucial for appropriate management and improved patient outcomes.
Abstract:
Asthma is the most common reason for children to present to an emergency department complaining of shortness of breath. The diagnosis, based on one or more of a positive history of atopy, physical examination findings consistent with reactive airways disease, and a clinical response to bronchodilator therapy is usually straightforward. It is important however, to consider other diagnoses, particularly when patients present differently from that which has previously been documented and/or have unexplained physical findings.
Related Concept Videos
Asthma: Pathogenesis and Management
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-II: Pathophysiology and Classification
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma-III: Symptoms and Complications
Classification of Asthma
Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma I: Introduction
Asthma III: Clinical Manifestations

