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The genome of Mycobacterium leprae: a minimal mycobacterial gene set
1Department of Microbiology, Colorado State University, Fort Collins, CO 80523, USA. Varalakshmi.Vissa@colostate.edu
Genome Biology
|September 5, 2001
Abstract:
Comparison of the recently sequenced genome of the leprosy-causing pathogen Mycobacterium leprae with other mycobacterial genomes reveals a drastic gene reduction and decay in M. leprae affecting many metabolic areas, exemplified by the retention of a minimal set of genes required for cell-wall biosynthesis.