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Related Concept Videos

The Spinal Cord01:54

The Spinal Cord

The spinal cord is the body’s major nerve tract of the central nervous system, communicating afferent sensory information from the periphery to the brain and efferent motor information from the brain to the body. The human spinal cord extends from the hole at the base of the skull, or foramen magnum, to the level of the first or second lumbar vertebra.
General Structure of a Vertebra01:30

General Structure of a Vertebra

A typical vertebra, with the exception of the sacrum and coccyx, consists of a body, a vertebral arch, and seven different projections termed processes. The anterior portion of the vertebrae, the body, supports about half the body’s weight. The vertebral bodies progressively increase in size and thickness from the cervical region to the lumbar region of the vertebral column. The intervertebral discs present between the bodies of adjacent vertebrae firmly unites them, forming a continuous column.
Spinal Cord: Gross Anatomy01:15

Spinal Cord: Gross Anatomy

The spinal cord resides within the protective confines of the vertebral column. It is the main pathway for information traveling between the brain and the body. It plays a fundamental role in nearly all bodily functions, from simple reflexes to complex motor movements. The spinal cord begins at the medulla oblongata at the base of the brainstem and extends downward, terminating at the conus medullaris near the first and second lumbar vertebrae. The spinal cord's length in adults is...
Spinal Cord: Cross-sectional Anatomy01:16

Spinal Cord: Cross-sectional Anatomy

The cross-sectional anatomy of the spinal cord offers a detailed view of its complex structure and function within the central nervous system. At the core of the spinal cord lies the gray matter, characterized by its butterfly or "H"-shaped appearance in cross-section. This central region is enveloped by white matter, with the overall structure divided into symmetrical halves by the dorsal median sulcus and the ventral median fissure.
Gray Matter and its Components
Central to the gray matter is...
Spinal Nerves: Anatomy01:23

Spinal Nerves: Anatomy

Spinal nerves are pivotal conduits in the nervous system, bridging the central nervous system (CNS) with the peripheral nervous system (PNS). These nerves enable a complex communication network between the brain, spinal cord, and the rest of the body, facilitating sensory input, motor output, and autonomic functions.
There are 31 bilateral pairs of spinal nerves, each emerging from the spinal cord through the intervertebral foramina—openings between adjacent vertebrae. These nerves are...
Spinal Nerves: Plexus II01:21

Spinal Nerves: Plexus II

The plexuses of the lower body include the lumbar, sacral, and coccygeal plexuses, which innervate the abdomen, pelvis, legs, and coccygeal region. These plexuses control the transmission of sensory information and coordinate motor functions of the lower body.
The Lumbar Plexus
The lumbar plexus is situated within the lumbar region of the back and is primarily formed by the first four lumbar spinal nerves (L1 to L4). This plexus extends its branches into several nerves, including the...

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Spinal Cord Lateral Hemisection and Asymmetric Behavioral Assessments in Adult Rats
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Spinal Cord Lateral Hemisection and Asymmetric Behavioral Assessments in Adult Rats

Published on: March 24, 2020

Banded structures in cauda equina.

C L Scholtz

    Pathology
    |April 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Fibrous long-spacing collagen was found in a cauda equina biopsy due to nerve compression. These banded structures resemble those in schwannomas, suggesting compression may trigger their formation.

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    Spinal Hernia Repair and Cauda Equina Repositioning After Lumbar Decompression under Three-Dimensional Microscopy: A Case Report and Literature Review
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    Spinal Hernia Repair and Cauda Equina Repositioning After Lumbar Decompression under Three-Dimensional Microscopy: A Case Report and Literature Review

    Published on: November 8, 2024

    Area of Science:

    • Neuropathology
    • Biochemistry
    • Spinal Cord Research

    Background:

    • Cauda equina compression can lead to various neuropathological changes.
    • Schwannomas and other conditions exhibit characteristic banded structures.
    • Fibrous long-spacing collagen (FLSC) is a collagen variant with unique ultrastructural features.

    Purpose of the Study:

    • To identify and characterize banded structures observed in a cauda equina biopsy from a patient with spinal nerve compression.
    • To compare these structures with known collagen types and pathological findings.

    Main Methods:

    • Cauda equina biopsy.
    • Histological and ultrastructural examination of the biopsy.
    • Comparison with established pathological and ultrastructural databases.

    Main Results:

    • Banded structures were identified in the cauda equina biopsy.
    • These structures were identical to those observed in schwannomas and other conditions.
    • The structures were identified as fibrous long-spacing collagen (FLSC).
    • FLSC exhibited a periodicity of approximately 1200 Å in relation to the basement membrane.
    • Substructure of FLSC could not be further elucidated.

    Conclusions:

    • The presence of FLSC in the cauda equina biopsy is linked to spinal nerve compression.
    • Compression is postulated as the initiating factor for FLSC formation in this context.
    • FLSC may be a common finding in neuropathies involving nerve compression.