Related Experiment Video
Updated: Oct 4, 2026

Murine Model of Thoracic Aortic Dissection Induced by Oral β-Aminopropionitrile and Subcutaneous Angiotensin II Infusion
Published on: May 16, 2025
Influence of gender on intraluminal thrombus of abdominal aortic aneurysms
H Yasuhara1, N Ohara, H Nagawa
1Department of Surgery, Teikyo University Ichihara Hospital, 3426-3 Anesaki, 299-0111, Ichihara City, Chiba, Japan. yasuhart-tky@umin.ac.jp
Background:
The mechanisms of formation of intraluminal thrombus (ILT) of abdominal aortic aneurysms (AAA) remain unknown. The aim of this study was to investigate the pathogenesis of AAA by analysis of ILT.
Methods:
We retrospectively analyzed the size of ILT in 98 consecutive patients with AAA undergoing abdominal computed tomography (CT) examination. The volume of ILT was estimated by the area ratio of ILT in CT images. Important baseline variables related to small ILT were determined using logistic-regression analysis.
Results:
There were two apparent peaks in the distribution of ILT ratio. Thirteen of 98 patients had negligible ILT with ratio < or = 0.1. Female gender was the only patient characteristic independently significantly correlated with small ILT (odds ratio 5.214, P = 0.0096).
Conclusion:
Our findings provide important evidence that AAA is formed by at least two different pathogenic processes. It is likely that this difference in mechanisms may be caused partly by sex hormones.
Related Concept Videos
Aneurysm III: Interprofessional Care
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Aneurysm I: Introduction
Abdominal Aorta
The celiac trunk, a singular artery, divides into the left gastric artery, which...

