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Related Experiment Videos

Bone marrow aspiration.

B J Bain1

  • 1Department of Haematology, St Mary's Hospital Campus of Imperial College School of Medicine, Praed Street, London, W2 1NY, UK. b.bain@ic.ac.uk

Journal of Clinical Pathology
|September 5, 2001
PubMed
Summary
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Bone marrow aspiration biopsies are crucial for detailed cytological and specialized investigations. Proper technique, site selection, and systematic reporting ensure accurate diagnostic assessments for patient care.

Area of Science:

  • Hematology
  • Pathology
  • Medical Diagnostics

Background:

  • Bone marrow aspiration biopsies are essential for diagnosing various hematological conditions.
  • These biopsies allow for cytological, immunophenotypic, cytogenetic, and molecular genetic analyses.
  • Often performed alongside trephine biopsies, they provide comprehensive diagnostic information.

Purpose of the Study:

  • To outline the indications, contraindications, and hazards of bone marrow aspiration.
  • To detail the standard operating procedures for trained personnel.
  • To emphasize the importance of systematic assessment and reporting for accurate diagnosis.

Main Methods:

  • Aspiration performed by trained individuals following a standard operating procedure.
  • Preferred site: posterior iliac crest for patient comfort and safety.

Related Experiment Videos

  • Preparation of marrow films, fixation, staining (Romanowsky and Perls' stains), and cover slip application.

    • Main Results:

    • Systematic assessment of bone marrow films using microscopy (low, intermediate, high power).
    • Performance of a differential count.
    • Interpretation of findings correlated with clinical and hematological features.

    Conclusions:

    • Bone marrow aspiration requires trained professionals aware of procedural nuances.
    • Systematic film assessment and timely, accurate reporting are critical for effective patient management.
    • Adherence to standard operating procedures ensures diagnostic quality and patient safety.