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Analysis of Mason-Pfizer monkey virus Gag particles by scanning transmission electron microscopy

S D Parker1, J S Wall, E Hunter

  • 1Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA.

Journal of Virology
|September 5, 2001
PubMed

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Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
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