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Primary hyperparathyroidism and pregnancy.
1Department of Medicine, King Khalid University Hospital, PO Box 2925, Riyadh 11461, Kingdom of Saudi Arabia.
Saudi Medical Journal
|September 5, 2001
Summary
Primary hyperparathyroidism in pregnancy is rare but risky. Early screening for this condition in women of childbearing age and during pregnancy is recommended to prevent complications for mother and child.
Area of Science:
- Endocrinology
- Obstetrics & Gynecology
Background:
- Primary hyperparathyroidism (PHP) is uncommon during pregnancy.
- It poses significant risks to both maternal and fetal health.
- Prompt diagnosis and management are crucial.
Purpose of the Study:
- To report on cases of primary hyperparathyroidism complicating pregnancy.
- To highlight the importance of early detection and intervention.
Main Methods:
- A retrospective review of patients diagnosed with primary hyperparathyroidism between 1982 and 1997.
- Identification of cases where PHP coexisted with pregnancy from hospital records.
Main Results:
- Three cases of primary hyperparathyroidism in pregnancy were identified over 16 years.
- Two patients had coexisting vitamin D deficiency and were initially misdiagnosed.
- One patient experienced an abortion, while the other two delivered healthy babies after parathyroid adenoma removal.
Conclusions:
- Primary hyperparathyroidism in pregnancy, though rare, presents substantial risks.
- Screening for asymptomatic PHP in women of childbearing age and pregnant women is advised.
- Early identification can mitigate severe maternal and fetal complications.