Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Thyroid function in cord blood.

G Henry1, S H Sobki, N M Al-Beshara

  • 1Department of Pathology, Riyadh Armed Forces Hospital, PO Box 7897, Riyadh 11159, Kingdom of Saudi Arabia.

Saudi Medical Journal
|September 5, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Refining delayed breast reconstruction with buried DIEP flaps: Toward a more direct and flexible approach.

Annales de chirurgie plastique et esthetique·2026
Same author

[The submental flap: Anatomical study of pedicle elongation].

Annales de chirurgie plastique et esthetique·2025
Same author

"They just knew, and that makes all the difference": Understanding positive healthcare experiences among trans people in Canada.

International journal of transgender health·2025
Same author

[Preoperative antibiotic prophylaxis and breast reduction surgery: A call for new recommendations].

Annales de chirurgie plastique et esthetique·2025
Same author

Functional and nutritional properties of fava bean ingredients processed by extrusion.

Food research international (Ottawa, Ont.)·2025
Same author

Reconstruction of a septic femoral triangle using a vertical pedicled DIEP flap: Response to the article "Reconstruction of a septic femoral triangle fistula with a pedicled DIEP flap: A case report and mini-review".

Annales de chirurgie plastique et esthetique·2024
Same journal

Molecular Mechanisms of Diffuse Large B-Cell Lymphoma and the Complexities of Tumor Development.

Saudi medical journal·2026
Same journal

Polysomnographic and Clinical Characteristics of Narcolepsy in Saudi Arabia: <i>A 12-Year Retrospective Study</i>.

Saudi medical journal·2026
Same journal

Etiology, Management, and Outcomes of Hospitalized Heart Failure Patients: <i>A Single-Center Study</i>.

Saudi medical journal·2026
Same journal

Effect of Anesthetic Agents on Middle Ear Pressure: Systematic Review and Meta-Analysis.

Saudi medical journal·2026
Same journal

Evaluation of Raqeem Health Information System in Primary Healthcare Centers in Makkah, Saudi Arabia, Using the DeLone and McLean Information System Success Model.

Saudi medical journal·2026
Same journal

Integrating Traditional and Complementary Medicine into Saudi Primary Care: <i>A Literature Review in Light of the WHO 2025-2034 Strategy</i>.

Saudi medical journal·2026
See all related articles

This study established thyroid function reference ranges in Saudi infant cord blood. Thyrotropin (TSH), free thyroxine (fT4), and thyroxine-binding globulin (TBG) ranges were similar to existing data, but free triiodothyronine (fT3) and thyroglobulin (Tg) differed.

Area of Science:

  • Endocrinology
  • Neonatal screening
  • Biochemistry

Background:

  • Thyroid function assessment in neonates is crucial for early detection of disorders.
  • Establishing local reference ranges ensures accurate interpretation of thyroid function tests in cord blood.

Purpose of the Study:

  • To determine the biochemical parameters of thyroid function in the cord blood of Saudi infants.
  • To establish local reference ranges for key thyroid hormones and binding proteins.

Main Methods:

  • Cord blood samples were analyzed for thyrotropin (TSH), free thyroxine (fT4), free triiodothyronine (fT3), thyroxine-binding globulin (TBG), and thyroglobulin (Tg).
  • Immunoassay techniques including Elisa, microparticle enzyme immunoassay, and chemiluminescence immunoassay were utilized.
  • Reference ranges were calculated following the exclusion of outliers.

Related Experiment Videos

Main Results:

  • Reference ranges for TSH, fT4, and TBG in Saudi infants were comparable to previously published values.
  • Reference ranges for fT3 and Tg in this population were found to be different from existing literature.
  • These findings highlight potential ethnic or methodological variations in thyroid hormone levels.

Conclusions:

  • Accurate interpretation of neonatal thyroid function necessitates population-specific reference ranges.
  • Local reference ranges, based on current laboratory methods, are essential for Saudi infants.
  • Discrepancies in fT3 and Tg ranges underscore the need for ongoing validation of laboratory standards.