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Donor human milk for preterm infants.

N E Wight1

  • 1Lactation Services, Sharp Mary Birch Hospital for Women, San Diego, CA 92123, USA.

Journal of Perinatology : Official Journal of the California Perinatal Association
|September 5, 2001
PubMed
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Pasteurized donor human milk offers benefits for preterm infants when mother's own milk is unavailable. It provides essential nutrients and may reduce healthcare costs associated with complications like necrotizing enterocolitis.

Area of Science:

  • Neonatal Nutrition
  • Human Milk Research
  • Infant Health

Background:

  • Improving survival rates for preterm infants necessitates optimal nutritional management.
  • Human milk is recognized for its benefits in term infants, with emerging evidence supporting its advantages for preterm infants.
  • Maternal provision of breast milk may not always be feasible for preterm infants.

Purpose of the Study:

  • To evaluate the role and benefits of pasteurized donor human milk (PDHM) for preterm infants.
  • To assess the nutritional and immunological components of PDHM compared to mother's own milk.
  • To analyze the cost-effectiveness of PDHM in neonatal intensive care units (NICUs).

Main Methods:

  • Review of current research on human milk for preterm infants.

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  • Analysis of the impact of pasteurization on the components of human milk.
  • Cost-benefit analysis comparing PDHM expenditure to potential healthcare savings.

    • Main Results:

    • PDHM retains many beneficial immunoglobulins, enzymes, hormones, and growth factors despite pasteurization.
    • While pasteurization affects some components, PDHM offers a safe alternative to mother's own milk, mitigating infectious agent transmission.
    • The use of PDHM may lead to significant cost savings for NICUs and healthcare plans.

    Conclusions:

    • Pasteurized donor human milk is a viable and beneficial option for preterm infants when mother's milk is unavailable.
    • PDHM provides crucial nutritional and immunological support, with manageable alterations from pasteurization.
    • Investing in PDHM can result in substantial cost reductions by decreasing NICU length of stay and managing common infant morbidities.