Related Experiment Video
Updated: Oct 4, 2026

Isolation of Primary Human Decidual Cells from the Fetal Membranes of Term Placentae
Published on: April 30, 2018
[Immunocompetent cells in decidual tissue in normal pregnancy and in cases of early miscarriages]
1I. M. Sechenov Moscow Medical Academy, 119881, Moscow.
Abstract:
Uterine scrapes from 45 women (30 cases of spontaneous and 15 cases of artificial abortions) were studied. Heterogeneity of distribution of large granular lymphocytes and macrophages in decidual membrane of women with spontaneous abortions was revealed. Autoimmune disturbances were found primarily in the subgroup with domination of large granular lymphocytes, urogenital infection prevailed in the subgroup with macrophage domination. Hormonal disturbances and uterine malformations occurred more frequently in women with normal count of lymphocytes and macrophages.
Related Concept Videos
Development of Immunocompetence
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Cytomegalovirus Disease
Embryonic Connective Tissues
The mesenchyme is the first connective tissue that emerges in the developing embryo. It consists of loosely arranged multipotent mesenchymal cells and reticular fibers in the extracellular matrix. This loose arrangement allows easy migration of cells, which is essential for germ layer positioning, patterning, and organ morphogenesis during embryonic development. Mesenchyme is...

