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[Method of calculating the equivalent tumor dose as a function as to irradiated tumor tissue volume]
Abstract:
Based on the assumption that tumor tissue consists of normal and radiation-resistant, that the survival of both types of tumor cells may be described by LQ functions and that the count of radiation-resistant cells is in proportion to that of tumor cells, the author has developed a method for calculating the equivalent tumor dose as a function as to irradiated tumor tissue volume for the fixed value of a single dose in the session of radiation. The developed formalism may be used to test the hypothesis that the count of clonogenic and radiation-resistant cells is in proportion to the baseline number of the cells in the tumor tissue.