Related Experiment Video
Updated: Oct 4, 2026

Reprogramming Pancreatic Ductal Adenocarcinoma to Pluripotency
Published on: February 2, 2024
[Central diabetes insipidus as clinical presentation of a bronchogenic adenocarcinoma]
M Boronat1, D Marrero, A Carrillo
1Sección de Endocrinología y Nutrición, Hospital Insular, Las Palmas de Gran Canaria.
Abstract:
Metastatic tumors of the pituitary gland are uncommon. The majority of them are silent lesions incidentally discovered at autopsy. In contrast, the occurrence of symptomatic metastases is exceptional. Here we report the clinical and radiological findings of a 45 year-old woman with a metastatic lung adenocarcinoma who presented with diabetes insipidus and hypernatremic dehydration. There was no previous history of malignancy, and the pituitary metastases were responsible for the first manifestation of the disease. Clinical presentation, diagnosis and therapeutic management of patients with pituitary metastases are reviewed.
Related Concept Videos
Diabetes Insipidus I: Introduction
Diabetes Insipidus II: Pathophysiology
Type I Diabetes III: Clinical Manifestations
Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis
Diabetic Ketoacidosis l: Introduction
Diabetes: Symptoms, Diagnosis, and Complications