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Cytotoxic T cell polyepitope vaccines delivered by ISCOMs

T T Le1, D Drane, J Malliaros

  • 1Cooperative Research Centre for Vaccine Technology, Australian National Centre for International and Tropical Health and Nutrition, Queensland Institute of Medical Research and the University of Queensland, Post Office Royal Brisbane Hospital, Brisbane.

Vaccine
|September 6, 2001
PubMed

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Antigens Involved in Adaptive Immunity

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Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
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