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[Gardner's syndrome. A case report].

M Ripari1, A Cicconetti, M Sed

  • 1Cattedra di Clinica Odontostomatologica, Università degli Studi La Sapienza, Rome, Italy.

Minerva Stomatologica
|September 6, 2001
PubMed
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Gardner's syndrome involves intestinal polyps and tumors, with improved survival increasing associated lesions like maxillary osteomas. This case highlights the syndrome's complex presentation and management.

Area of Science:

  • Medical Genetics
  • Oncology
  • Ophthalmology

Background:

  • Gardner's syndrome is a rare congenital disorder.
  • Characterized by diffuse intestinal adenomatous polyposis (IAP).
  • Associated with extracolonic manifestations including osteomas and skin tumors.

Observation:

  • A case of Gardner's syndrome was observed at the Odontostomatological Clinic, University of Rome La Sapienza.
  • The patient presented with characteristic features of the syndrome.
  • Focus on the dental and craniofacial manifestations.

Findings:

  • Diffuse intestinal adenomatous polyposis (IAP) is the most serious clinical aspect.
  • Surgical treatment of IAP has improved patient survival rates.
  • Increased survival has led to a higher incidence of associated lesions, notably maxillary osteomas.

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Implications:

  • Enhanced survival necessitates vigilant monitoring for extracolonic manifestations.
  • Maxillary osteomas are a significant associated lesion requiring attention.
  • Understanding the syndrome's progression is crucial for comprehensive patient care.