Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pulmonary veno-occlusive disease.

U Thadani, C Burrow, W Whitaker

    The Quarterly Journal of Medicine
    |January 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Influence of contaminants of emerging concern on the primary and secondary metabolites of hydroponically grown tomatoes.

    Food chemistry·2025
    Same author

    Contaminants of emerging concern: Silylation procedures, evaluation of the stability of silyl derivatives and associated measurement uncertainty.

    The Science of the total environment·2023
    Same author

    Serology and longevity of immunity against Echinococcus granulosus in sheep and llama induced by an oil-based EG95 vaccine.

    Parasite immunology·2016
    Same author

    The radiological manifestations of pulmonary hypertension in patients with mitral stenosis.

    The Journal of the Faculty of Radiologists. Faculty of Radiologists (Great Britain)·2014
    Same author

    Pulmonary ossification in patients with mitral stenosis.

    The Journal of the Faculty of Radiologists. Faculty of Radiologists (Great Britain)·2014
    Same author

    Cardiopulmonary exercise testing predicts postoperative outcome in patients undergoing gastric bypass surgery.

    British journal of anaesthesia·2012

    Pulmonary veno-occlusive disease (PVOD) is a fatal cause of pulmonary arterial hypertension. Diagnosis can be challenging, often requiring histological confirmation due to overlapping symptoms with other conditions.

    Area of Science:

    • Cardiology
    • Pulmonary Medicine
    • Pathology

    Background:

    • Pulmonary veno-occlusive disease (PVOD) is a rare condition causing pulmonary arterial hypertension.
    • It is characterized by insidious onset, progressive nature, and a poor prognosis due to lack of effective treatment.
    • Early symptoms like breathlessness can be misdiagnosed as anxiety states.

    Purpose of the Study:

    • To review reported cases and a new patient with pulmonary veno-occlusive disease.
    • To highlight diagnostic challenges and differentiate PVOD from other pulmonary hypertension causes.
    • To describe the pathological features of PVOD.

    Main Methods:

    • Review of twenty previously reported cases and one new patient.
    • Clinical assessment including symptoms, signs, and diagnostic imaging (pulmonary angiography, lung scanning).

    Related Experiment Videos

  • Histopathological examination of lung tissue to identify characteristic venous lesions.

    • Main Results:

    • PVOD presents with breathlessness and signs of pulmonary arterial hypertension.
    • Some patients exhibit signs of pulmonary venous and capillary hypertension, aiding diagnosis when left atrial pressure is normal.
    • Histology reveals widespread occlusion of pulmonary veins by intimal fibrosis, often with recanalization.

    Conclusions:

    • Pulmonary veno-occlusive disease is a distinct pathological entity causing pulmonary arterial hypertension.
    • Clinical recognition is possible in some cases, but histological confirmation is often necessary.
    • The disease is invariably fatal, with a median survival of approximately two years post-diagnosis.