Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Non-invasive densitometry.

P Lips1

  • 1Department of Endocrinology, Free University Hospital, Amsterdam, The Netherlands.

Acta Astronautica
|July 1, 1992
PubMed
Summary
This summary is machine-generated.

Non-invasive bone density measurement methods like DXA and pQCT are crucial for monitoring bone loss during bed rest or microgravity. These techniques offer precision and low radiation exposure, aiding in skeletal health research.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Is it time to consider population screening for fracture risk in postmenopausal women? A position paper from the International Osteoporosis Foundation Epidemiology/Quality of Life Working Group.

Archives of osteoporosis·2022
Same author

Clinical osteoarthritis of the hip and knee and fall risk: The role of low physical functioning and pain medication.

Seminars in arthritis and rheumatism·2020
Same author

Vitamin D and metabolic disturbances in polycystic ovary syndrome (PCOS): A cross-sectional study.

PloS one·2018
Same author

Association of renal function with bone mineral density and fracture risk in the Longitudinal Aging Study Amsterdam.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2018
Same author

Prediction of insufficient serum vitamin D status in older women: a validated model.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2018
Same author

The relationship between serum IGF-1, handgrip strength, physical performance and falls in elderly men and women.

European journal of endocrinology·2018
Same journal

Rendering knowledge graphs from aerospace dentistry processes for clinical decision support systems.

Acta astronautica·2025
Same journal

Interstellar space biology via Project Starlight.

Acta astronautica·2023
Same journal

How businesses are working together to deliver NASA/JPL-designed ventilators to the world in the fight against COVID-19.

Acta astronautica·2022
Same journal

A Geospatial Artificial Intelligence and satellite-based earth observation cognitive system in response to COVID-19.

Acta astronautica·2022
Same journal

Isolation and confinement due to the COVID-19 pandemic: Lessons for human spaceflight.

Acta astronautica·2022
Same journal

Data-driven CFD Scaling of Bioinspired Mars Flight Vehicles for Hover.

Acta astronautica·2022
See all related articles

Area of Science:

  • Orthopedics
  • Radiology
  • Biomedical Engineering

Background:

  • Bedrest and microgravity induce significant bone loss, particularly in lower skeletal regions.
  • Monitoring skeletal changes is vital for understanding physiological adaptations and developing countermeasures.
  • Non-invasive techniques are essential for longitudinal studies of bone density changes.

Purpose of the Study:

  • To review and compare non-invasive methods for measuring bone density.
  • To highlight the suitability of different techniques for studying bone loss in specific conditions like microgravity.
  • To discuss the precision, radiation exposure, and capabilities of various bone densitometry methods.

Main Methods:

  • Single photon absorptiometry (SPA) for forearm and calcaneus.

Related Experiment Videos

  • Dual energy X-ray absorptiometry (DXA) for widespread skeletal region assessment.
  • Peripheral quantitative computed tomography (pQCT) for detailed forearm and tibia analysis, including cortical and trabecular bone.
  • Ultrasound assessment of calcaneus for bone density and structure evaluation.

    • Main Results:

    • DXA offers good precision with minimal radiation exposure across most skeletal sites.
    • pQCT provides precise measurements with low radiation dose and can differentiate cortical and trabecular bone, important for microgravity research.
    • Ultrasound techniques show promise, correlating with BMD and offering radiation-free assessment, though clinical utility requires further validation.

    Conclusions:

    • Non-invasive bone densitometry methods vary in precision, skeletal coverage, and ability to assess bone compartments.
    • DXA and pQCT are established, reliable techniques for monitoring bone loss.
    • Emerging ultrasound technologies present a radiation-free alternative, pending further clinical validation for bone density assessment.