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Effect of pentoxifylline on energy rich phosphates in rat's erythrocytes
Research Communications in Chemical Pathology and Pharmacology
|April 1, 1975
Abstract:
After an oral administration of 5 mg/kg pentoxifylline (3, 7-dimethyl-1-(5-oxo-hexyl)-xanthine, Trental -R) increases significantly total adenine nucleotides content, ATP and AMP, and decreases significantly ADP in rat's erythrocytes. This increased ATP level is likely partly responsible for the therapeutic effect of pentoxifylline in the disturbed peripheral circulation.