Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Versatile fluid-mixing device for cell and tissue microgravity research applications.

W W Wilfinger1, C S Baker, E L Kunze

  • 1Pennyslvania State University, University Park 16802, USA.

Journal of Spacecraft and Rockets
|January 1, 1996
PubMed
Summary

The Biomodule is a versatile, computer-controlled fluid-mixing device designed for microgravity life-science research. Its adaptable hardware and cell encapsulation methods streamline experiments and analysis in space.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Leveraging Synteny to Generate Reference Genomes for Conservation: Assembling the Genomes of Hector's and Māui Dolphins.

Molecular ecology resources·2025
Same author

Author Correction: Universal DNA methylation age across mammalian tissues.

Nature aging·2023
Same author

Universal DNA methylation age across mammalian tissues.

Nature aging·2023
Same author

Variation in blubber cortisol levels in a recovering humpback whale population inhabiting a rapidly changing environment.

Scientific reports·2022
Same author

Demography of an ice-obligate mysticete in a region of rapid environmental change.

Royal Society open science·2022
Same author

Adalimumab for nail psoriasis: efficacy and safety over 52 weeks from a phase-3, randomized, placebo-controlled trial.

Journal of the European Academy of Dermatology and Venereology : JEADV·2019

Area of Science:

  • Space life sciences
  • Biotechnology
  • Experimental hardware development

Background:

  • Microgravity research demands adaptable experimental hardware.
  • Existing systems may lack flexibility for diverse life-science investigations.
  • The need for controlled environments in space-based biological studies is critical.

Purpose of the Study:

  • To introduce the Biomodule, a novel fluid-mixing device for microgravity life-science research.
  • To highlight its capabilities in accommodating diverse experimental designs and environments.
  • To present an integrated system for space-based biological investigations.

Main Methods:

  • Utilizing a patented, computer-controlled fluid-mixing device (Biomodule).
  • Employing gas-permeable Silastic T tubes within fluid-filled compartments for sample containment.

Related Experiment Videos

  • Integrating the Biomodule with a sealed containment vessel and NASA refrigeration-incubation module.
  • Developing a cell microencapsulation methodology for streamlined sample handling.

    • Main Results:

    • The Biomodule system supports multiple investigators and complex experimental designs.
    • It provides a sealed, controlled environment with regulated temperature, pressure, humidity, and gas composition.
    • Cell microencapsulation facilitates efficient launch-site preparation and postflight analysis via fluorescent-activated cell sorting.

    Conclusions:

    • The Biomodule flight hardware offers a flexible and robust platform for microgravity life-science research.
    • The integrated cell encapsulation methodology enhances experimental efficiency from sample preparation to analysis.
    • This system is well-suited for temporal, qualitative, and quantitative life-science investigations in space.