CROCODILE: an automated apparatus for organic crystal growth from solution
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Updated: Oct 4, 2026

Growing Protein Crystals with Distinct Dimensions Using Automated Crystallization Coupled with In Situ Dynamic Light Scattering
Published on: August 14, 2018
F Gonzalez1, M Cunisse, A Perigaud
1CNES, Toulouse, France.
Abstract:
CROCODILE (CROissance de Cristaux Organiques par DIffusion Liquide dans l'Espace) is a space instrument dedicated to crystal growth from solution. The selected material N (4 nitrophenyl) (L) prolinol (NPP) is the result of studies on organic crystal in the frame of an extended program initiated by CNES for many years. The apparatus was flown aboard PHOTON, an automatic satellite, in April 1990, for a flight duration of more than 15 days. This paper describes the instrument design, with emphasis on specific and original technology well adapted to crystal growth from solution, and extendible to any space experiment on fluids. Preliminary details of the flight campaign will also be discussed.
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