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[Relation of GFR and endothelin in the plasma in pilots and ground crew]
Objective:
To observe the specitic property of Glomeoular Filtration Rate (GFR) and its relation to endothelin of plasma in pilots.
Method:
GFR was assessed with single photon emisson computed tomography (SPECT), tracer for 99mTc-DTPA, enthlion of plasma were measured by radio immunossay in forty-six pilots, thirty ground crew and renal disease patients.
Result:
Endothelin were not correlation with GFR in pilots. GFR of pilots and ground crew had not a significant difference. Compared with ground crew and pilots, endothelin of renal disease patients had a significant increased, and GFR had a significant decreased. Age were a linear negative correlation with total GFR r = (0.84, P < 0.01), flying time, age had not correlation with endothelin. After thirty-one ground endothelin had a significant difference with ground crew.
Conclusion:
It suggested that the endothelin has no influence on GFR in pilots when it was increased with in the limits of a level, pilots and ground crew may use the same stand on GFR.
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