A proof of principle for targetry to produce ultra high quantities of 18F-fluoride
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Updated: Oct 4, 2026

09:57
18F-Labeling of Radiotracers Functionalized with a Silicon Fluoride Acceptor (SiFA) for Positron Emission Tomography
Published on: January 11, 2020
T J Ruth1, K R Buckle, K S Chun
1PET Chemistry, TRIUMF, Vancouver, BC, Canada. truth@triumf.ca
Abstract:
The production of 18F-fluoride from a gas target which utilizes the (18)O(p,n)18F reaction is described. Proof-of-principle experiments demonstrate that it is possible to design and build such a target that can be used routinely to produce terabecquerel (curie) quantities of 18F when operated at 100 microA.
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