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Optic perineuritis: clinical and radiographic features
V Purvin1, A Kawasaki, D M Jacobson
1Midwest Eye Institute, 201 Pennsylvania Pkwy, Indianapolis, IN 46280, USA. Vpurvin@iupui.edu
Archives of Ophthalmology (Chicago, Ill. : 1960)
|September 27, 2001
Summary
Idiopathic optic perineuritis, an uncommon orbital inflammation, often affects older adults and presents with preserved central vision. Magnetic resonance imaging shows enhancement around the optic nerve, responding dramatically to corticosteroids but with a risk of recurrence.
Area of Science:
- Ophthalmology
- Neuro-ophthalmology
- Inflammatory diseases
Background:
- Optic perineuritis is a rare orbital inflammatory condition distinct from optic neuritis.
- Understanding its unique characteristics is crucial for accurate diagnosis and management.
Observation:
- A study reviewed 14 patients diagnosed with idiopathic optic perineuritis.
- Patients experienced visual loss and/or eye pain, with varied visual acuity and visual field defects.
Findings:
- Idiopathic optic perineuritis typically presents in older individuals (24-60 years) with visual loss and eye pain.
- Magnetic resonance imaging revealed circumferential optic nerve enhancement, differentiating it from optic neuritis.
- Treatment with corticosteroids yielded dramatic responses, though relapses occurred upon dose reduction.
Implications:
- Optic perineuritis differs from optic neuritis in patient age, visual acuity preservation, and MRI findings.
- The condition shows a strong response to corticosteroids but a higher likelihood of recurrence.
- Distinguishing optic perineuritis from optic neuritis is vital for appropriate therapeutic strategies.