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Updated: Oct 4, 2026

Assessing Activity-based Anorexia in Mice
Published on: May 14, 2018
[Anorexia nervosa or somatic disease]
J García Aroca1, J L Alonso Calderón, C García Redondo
1Servicio de Cirugía Pediátrica, Hospital Niño Jesús, Avda. Menéndez Pelayo 65, 28009 Madrid.
Abstract:
We have studied 18 patients with anorexia nervosa with antroduodenal manometry for 24 hours and also 24 hours oesophageal pH studies. After the first 12 hours of measurements we started treatment with Cisapride (n = 8) or Erythromycin (n = 10) in a blind study. The results of measurements reveal a severe gastroesophageal reflux in 4 patients. Antroduodenal manometry showed dysfunctions in gastric motility, without relation with weight loss or duration of the disease. Cisapride and more so Erythromycin favor gastrointestinal motility.
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