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Diffusion- and perfusion-weighted MRI in therapeutic neurointerventional procedures
M Cronqvist1, B Ramgren, B Geijer
1Department of Radiology, Lund University Hospital, Sweden. mats.cronqvist@drad.lu.se
Abstract:
We describe three patients in whom we used MRI, including diffusion- and perfusion-weighted imaging (DWI, PWI) in conjunction with endovascular therapy. Two had intracranial aneurysms and one an arteriovenous malformation (AVM). The aneurysms were treated by coil embolisation or detachable balloons for proximal artery occlusion; the AVM was obliterated by intranidal glue injection. All patients had transient or permanent neurological deficits after treatment. The MRI techniques and interventional procedures are described and the DWI and PWI patterns found are correlated with the clinical features. We discuss how the information gained from MRI may increase our understanding of procedure-related complications and its potential impact on our therapeutic interventions, in order to prevent or limit the clinical consequences of such events.
Insights
This study explores MRI, including diffusion- and perfusion-weighted imaging (DWI, PWI), to understand neurological deficits after endovascular therapy for intracranial aneurysms and arteriovenous malformations (AVMs). MRI insights may help prevent or limit complications from these neurointerventional procedures.
Area of Science:
- Neuroradiology
- Interventional Neurology
- Neuroimaging
Background:
- Endovascular therapy is a key treatment for intracranial aneurysms and arteriovenous malformations (AVMs).
- Neurological deficits can occur as complications following these neurointerventional procedures.
Observation:
- Three patients undergoing endovascular treatment for intracranial aneurysms or AVMs were evaluated using MRI, including diffusion- and perfusion-weighted imaging (DWI, PWI).
- Two patients had intracranial aneurysms treated with coil embolization or balloons; one had an AVM treated with glue injection.
- All patients experienced transient or permanent neurological deficits post-treatment.
Findings:
- Specific DWI and PWI patterns were observed and correlated with the clinical features of the neurological deficits.
- The study details the MRI techniques and interventional procedures employed.
Implications:
- Understanding MRI patterns associated with complications can improve patient outcomes.
- This neuroimaging approach may guide therapeutic interventions to prevent or mitigate neurological deficits.
- Enhanced comprehension of procedure-related complications through advanced MRI can refine neurointerventional strategies.