Related Experiment Video
Updated: Oct 4, 2026

Modeling Healthy and Dysbiotic Vaginal Microenvironments in a Human Vagina-on-a-Chip
Published on: February 16, 2024
[Vaginal microflora in girls of prepuberal age]
A V Boĭko1, V A Aleshkin, S S Afanas'ev
1State Medical Academy, Astrakhan, Gabrichevsky Research Institute of Epidemiology and Microbiology, Research Center of Obstetrics, Gynecology and Perinatology, Moscow, Russia.
Abstract:
The bacteriological study of vaginal microflora in 24 clinically healthy girls aged 7-8 years was carried out. Two criteria of normal vaginal biocenosis in girls of prepuberal age were proposed. The proportion of hemolytic bacteria in the vagina of a girl of prepuberal age could reach 100% of all microflora, provided the total bacterial count (TBC) exceed average values. A high proportion of hemolytic bacteria in the vaginal microflora of girls of prepuberal age in combination with a high level of TBC (even with TBC not exceeding the upper limit of its normal value) could probably by regarded as a border state. No fungi of the genus Candida should be isolated from vagina in girls of prepuberal age. Facultative anaerobic microflora was represented mainly by Staphylococcus epidermidis and S. saprophyticus. In 64.3 +/- 12.8% of cases bifidobacteria were detected in the girls vagina.
Related Concept Videos
Microbiota of the Urogenital Tract
Development of Human Microbiota
Vagina
Development of the Oral Microbiota
Surface Membrane Barriers
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
Candidiasis

