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Stereospecific synthesis of trans-arachidonic acids
U M Krishna1, M M Reddy, J Xia
1Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Bioorganic & Medicinal Chemistry Letters
|September 11, 2001
Abstract:
An effective synthesis is described for the preparation of all four mono trans isomers of arachidonic acid via deoxidation of epoxide precursors with lithium diphenylphosphide and quaternization with methyl iodide.
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