Related Experiment Video
Updated: Aug 18, 2026

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
Published on: September 25, 2009
Infectious aneurysm clipping by an MRI/MRA wand-guided protocol. A case report and technical note
1Department of Neurosurgery, University of Pittsburgh, Lothrop Street, Pittsburgh, PA 15213-2582, USA. aharris@neuronet.pitt.edu
Abstract:
Infectious aneurysms are potentially deadly sequelae of multiple etiologies, typically associated with subacute bacterial endocarditis (SBE). Since these aneurysms tend to be distal, there are no consistent landmarks by which to localize them, in contrast to more typical aneurysms that occur on the circle of Willis or proximal, large cerebral vessel bifurcations. In addition, they tend to be extremely friable and may be obscured by blood if intracranial hemorrhage (ICH) has already occurred. These factors make clipping these aneurysms technically difficult, and searching for easily ruptured aneurysms without standard landmarks adds risk to the procedure. In this report, we describe the case of a 9-year-old boy with SBE and subsequent ICH secondary to a mycotic aneurysm. This aneurysm was localized to within millimeters by the MRI protocol described herein. The aneurysm was excised and the patient recovered without incident. Thus, MRI/MRA-guided frameless stereotaxy may be useful for localizing distal mycotic aneurysms, improving patient outcome by decreasing morbidity and mortality.
Insights
This study highlights a novel MRI protocol for precisely locating distal mycotic aneurysms, often associated with subacute bacterial endocarditis. This technique aids surgical excision, improving outcomes for patients with infectious intracranial aneurysms.
Area of Science:
- Neurology
- Radiology
- Vascular Surgery
Background:
- Infectious aneurysms, often linked to subacute bacterial endocarditis (SBE), pose significant mortality risks.
- Distal locations and friability complicate surgical management of these aneurysms.
- Intracranial hemorrhage (ICH) can further obscure these challenging lesions.
Observation:
- A 9-year-old boy with SBE experienced intracranial hemorrhage due to a mycotic aneurysm.
- A specialized MRI protocol precisely localized the distal mycotic aneurysm.
- The aneurysm was successfully excised following accurate localization.
Findings:
- MRI/MRA-guided frameless stereotaxy offers millimeter-level precision for localizing distal mycotic aneurysms.
- This advanced imaging approach facilitates technically difficult aneurysm excision.
- The described MRI protocol can be a valuable tool in managing complex infectious aneurysms.
Implications:
- Improved localization of distal mycotic aneurysms can significantly decrease surgical risks.
- This technique has the potential to reduce morbidity and mortality associated with infectious aneurysms.
- Frameless stereotaxy guided by MRI/MRA may enhance patient outcomes in neurovascular surgery.
More Related Videos
Related Concept Videos
Magnetic Resonance Imaging
Imaging Studies for Cardiovascular System IV: CMRI

