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Related Experiment Videos

Plasma tocopherol in infants and children.

W R McWhirter

    Acta Paediatrica Scandinavica
    |May 1, 1975
    PubMed
    Summary

    Plasma tocopherol levels correlate positively with age in children. Children with cystic fibrosis or coeliac disease often exhibit significantly lower vitamin E levels compared to healthy peers.

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    Area of Science:

    • Pediatric Nutrition
    • Gastroenterology
    • Biochemistry

    Background:

    • Plasma tocopherol (vitamin E) is crucial for health.
    • Intestinal abnormalities can impact nutrient absorption.
    • Understanding vitamin E status in pediatric populations is important.

    Purpose of the Study:

    • To investigate plasma tocopherol concentrations in healthy children.
    • To compare vitamin E levels in children with intestinal disorders versus controls.
    • To determine the relationship between age and plasma tocopherol in children.

    Main Methods:

    • Plasma samples were collected from normal children and those with intestinal abnormalities.
    • Tocopherol concentrations were measured using biochemical assays.
    • Data were analyzed to assess correlations with age and disease status.

    Main Results:

    • A positive correlation was observed between plasma tocopherol and age in children aged 4 months to 10 years.
    • Children with cystic fibrosis or coeliac disease showed markedly reduced plasma tocopherol concentrations.
    • Significant differences in vitamin E status were found between patient groups and healthy children.

    Conclusions:

    • Age is a significant factor influencing plasma tocopherol levels in children.
    • Cystic fibrosis and coeliac disease are associated with impaired vitamin E status.
    • Monitoring vitamin E levels is recommended for children with these intestinal conditions.

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