Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Medical management of primary hyperaldosteronism.

E L Bravo1

  • 1Department of Nephrology and Hypertension, Cleveland Clinic Foundation, 9500 Euclid Avenue, Desk A51, Cleveland, OH 44195, USA.

Current Hypertension Reports
|September 12, 2001
PubMed
Summary

Medical management effectively treats primary aldosteronism when surgery isn't an option. Understanding hypertension mechanisms is key for successful treatment, even in complex cases.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical utility of temozolomide in the treatment of malignant paraganglioma: a preliminary report.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme·2009
Same author

Laparoscopic right adrenalectomy after liver transplantation.

Transplantation·2001
Same author

Pheochromocytoma coexisting with renal artery lesions.

The Journal of urology·2000
Same author

Laparoscopic adrenalectomy for large-volume (> or = 5 cm) adrenal masses.

Journal of endourology·2000
Same author

Anesthetic aspects of laparoscopic and open adrenalectomy for pheochromocytoma.

Urology·2000
Same author

Outpatient adrenalectomy.

The Journal of urology·2000

Area of Science:

  • Endocrinology
  • Nephrology
  • Cardiovascular Medicine

Background:

  • Primary aldosteronism is a common cause of secondary hypertension.
  • Surgical correction is often curative for adrenal adenomas.
  • Medical management is an alternative when surgery is not feasible.

Purpose of the Study:

  • To review the medical management of primary aldosteronism.
  • To highlight the importance of understanding hypertension mechanisms in this condition.
  • To discuss the long-term efficacy and safety of medical therapy.

Main Methods:

  • Literature review of primary aldosteronism management.
  • Analysis of pathophysiologic mechanisms of aldosterone excess.
  • Evaluation of clinical outcomes in medically treated patients.

Main Results:

  • Medical management is as effective as surgery for correcting aldosterone excess abnormalities.
  • Persistent hypervolemia is the main driver of resistant hypertension in primary aldosteronism.
  • Long-term medical treatment (5-7 years) shows sustained efficacy without adverse events.

Conclusions:

  • Medical management is a viable and effective alternative to surgery for primary aldosteronism.
  • Targeting hypervolemia is crucial for managing resistant hypertension.
  • Patients can be safely managed medically long-term, avoiding malignant transformation.

Related Experiment Videos