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Producing proteins in transgenic plants and animals.
1Planet Biotechnology, Inc., 2438 Wyandotte Street, Mountain View, CA 94043, USA. jwlarrick@aol.com
Current Opinion in Biotechnology
|September 12, 2001
Summary
Plants and animals are increasingly used as natural bioreactors for producing large quantities of therapeutic proteins. This approach has seen commercial success, with future potential for a wide range of protein products.
Area of Science:
- Biotechnology
- Molecular Biology
- Biochemistry
Background:
- Growing demand for therapeutic proteins necessitates efficient and scalable production methods.
- Traditional protein production systems face limitations in cost and scalability.
Purpose of the Study:
- To explore the potential of using plants and animals as bioreactors for recombinant protein production.
- To highlight the commercial success and future prospects of this biotechnology.
Main Methods:
- Utilizing genetically modified plants and animals for the synthesis of therapeutic proteins.
- Leveraging established molecular biology techniques for protein expression and purification.
Main Results:
- Successful commercialization of the first wave of recombinant proteins produced in these systems.
- Demonstrated viability and scalability of 'natural' bioreactors for biopharmaceutical manufacturing.
Conclusions:
- Plants and animals offer a promising and sustainable platform for the large-scale production of therapeutic proteins.
- The 'natural' bioreactor approach is poised for significant growth in the biopharmaceutical industry.