Hyperperfusion of anterior cingulate gyrus in a case of paroxysmal nocturnal dystonia
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Updated: Oct 4, 2026

Investigating The Network-Wide Mechanisms of Pallidal Deep Brain Stimulation Using High-Density Microelectrode Arrays
Published on: June 16, 2026
K Schindler1, H Gast, C Bassetti
1Department of Neurology, University of Berne, Inselspital, Switzerland. kschindler@access.ch
Abstract:
The authors report the clinical, EEG, and SPECT findings of a patient with nocturnal paroxysmal dystonia. Ictal and interictal scalp EEG showed epileptiform activity over both frontal lobes. Subtraction ictal SPECT co-registered to MRI indicated a bilateral significant hyperperfusion in the anterior part of the cingulate gyrus. These results support earlier electrophysiologic investigations by others suggesting that anterior cingulate epilepsy may manifest as nocturnal paroxysmal dystonia, and illustrate the usefulness of computer-assisted SPECT analysis.
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