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Dopaminergic therapy with carbidopa L-dopa for left neglect after stroke: a case series
J A Mukand1, T J Guilmette, D G Allen
1Southern New England Rehabilitation Center, Providence, RI 02907, USA.
Objective:
To evaluate the efficacy of carbidopa L-dopa (Sinemet) in reducing left spatial neglect after stroke.
Design:
Case series.
Setting:
Inpatient neurorehabilitation unit in a regional rehabilitation center.
Participants:
A convenience sample of 4 women with right brain strokes and left neglect.
Intervention:
A trial of carbidopa L-dopa to treat left neglect, if indicated by selected subtests of the Behavioral Inattention Test (BIT).
Main Outcome Measures:
Baseline and posttreatment evaluation with the modified BIT and the FIM instrument.
Results:
Three of 4 subjects had significant improvements in their modified BIT scores (8%, 12%, 27%, respectively) and their functional status on the FIM.
Conclusion:
With further study, carbidopa L-dopa may be shown to reduce unilateral spatial neglect and thereby improve rehabilitation outcomes.
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