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Updated: Aug 11, 2026

10:44
Expansion, Purification, and Functional Assessment of Human Peripheral Blood NK Cells
Published on: February 2, 2011
[Increase in NK-activity using superlow doses of the immunomodulator cycloferon]
E V Shevchenko1, B B Finkel'shteĭn, V A Ivanov
1Institute of Cytology RAS, St. Petersburg. shev@svs.ru
Tsitologiia
|September 13, 2001
Abstract:
A possibility of rising the antitumor activity of natural killers using various doses of the immunomodulator cycloferon was evaluated. A direct correlation has been revealed between the killer activity and the cycloferon dose. However, on a decrease in cycloferon concentrations by several orders, as compared with commonly accepted doses, this correlation changed for inverse. A possible mechanism of this effect is discussed in addition to practical significance of the obtained results.

