Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Dendrodendritic gap junctions: a developmental approach.

K Mollgård, M Moller

    Advances in Neurology
    |January 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The E3 ubiquitin ligase SMURF1 regulates cell-fate specification and outflow tract septation during mammalian heart development.

    Scientific reports·2018
    Same author

    Reply: Methodological considerations in measuring different AMH splice forms using ELISA: validity of proAMH ELISA.

    Molecular human reproduction·2016
    Same author

    Proteolytic processing of anti-Müllerian hormone differs between human fetal testes and adult ovaries.

    Molecular human reproduction·2015
    Same author

    The histochemical and ultrastructural basis of the cellular function of the human foetal adenohypophysis.

    Progress in histochemistry and cytochemistry·2012
    Same author

    SPARC/osteonectin, an endogenous mechanism for targeting albumin to the blood-cerebrospinal fluid interface during brain development.

    The European journal of neuroscience·2011
    Same author

    No evidence for the presence of oogonia in the human ovary after their final clearance during the first two years of life.

    Human reproduction (Oxford, England)·2011
    Same journal

    Future and alternative therapies in Tourette syndrome.

    Advances in neurology·2006
    Same journal

    Behavioral neurosurgery.

    Advances in neurology·2006
    Same journal

    Behavior therapy: other interventions for tic disorders.

    Advances in neurology·2006
    Same journal

    Behavioral treatments for tic suppression: habit reversal training.

    Advances in neurology·2006
    Same journal

    Treatment of aggression in Tourette syndrome.

    Advances in neurology·2006
    Same journal

    Treatment of co-morbid obsessive compulsive disorder, mood, and anxiety disorders.

    Advances in neurology·2006
    See all related articles

    Dendrodendritic gap junctions, crucial for neuronal communication, were identified in developing human neocortex. These junctions may facilitate electrotonic coupling and influence brain development.

    Area of Science:

    • Neuroscience
    • Developmental Biology
    • Cell Biology

    Background:

    • Dendrodendritic gap junctions are specialized cell junctions between neuronal dendrites.
    • Previous studies identified these junctions in adult rabbits and fetal sheep.
    • Alcian blue and freeze-fracture techniques are used to study gap junctions.

    Purpose of the Study:

    • To examine dendrodendritic gap junctions in the human fetal neocortex.
    • To describe the features of developing dendrodendritic gap junctions.
    • To discuss the functional significance of these junctions in the developing brain.

    Main Methods:

    • Examination of freeze-cleaved specimens of human fetal neocortex.
    • Utilizing Alcian blue as a marker substance for gap junction identification.

    Related Experiment Videos

  • Analysis of the morphological characteristics of dendrodendritic contacts.

    • Main Results:

    • Dendrodendritic gap junctions were identified in the human fetal neocortex.
    • The freeze-fracture appearance confirmed the presence of gap junctions.
    • Specific features of these developing junctions were described.

    Conclusions:

    • Dendrodendritic gap junctions provide electrotonic coupling for neurons within columnar organizations.
    • These junctions are suggested to play a role in cell differentiation and morphogenesis of the cerebral wall.