Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Metabolic studies in physically outstanding elderly men.

S Szanto

    Age and Ageing
    |February 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Regular vigorous exercise in elderly men is linked to lower insulin levels and improved growth hormone response during glucose tolerance tests. This suggests exercise positively impacts metabolic and hormonal regulation in older adults.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Effects of one-year tofacitinib therapy on bone metabolism in rheumatoid arthritis.

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2021
    Same author

    Comparison of peripheral quantitative computed tomography forearm bone density versus DXA in rheumatoid arthritis patients and controls.

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2016
    Same author

    Treatment of ankylosing spondylitis with biologics and targeted physical therapy: positive effect on chest pain, diminished chest mobility, and respiratory function.

    Zeitschrift fur Rheumatologie·2013
    Same author

    Efficacy of etanercept on rheumatic signs and pulmonary function tests in advanced ankylosing spondylitis: results of a randomised double-blind placebo-controlled study (SPINE).

    Annals of the rheumatic diseases·2011
    Same author

    Smoking and atherosclerosis.

    British medical journal·2010
    Same author

    Comparison of the Psoriatic Arthritis Quality of Life (PsAQoL) questionnaire, the functional status (HAQ) and utility (EQ-5D) measures in psoriatic arthritis: results from a cross-sectional survey.

    Scandinavian journal of rheumatology·2010
    Same journal

    Overlapping premorbid frailty, multimorbidity and malnutrition and their associations with poor outcomes in patients with stroke.

    Age and ageing·2026
    Same journal

    Overall and cause-specific mortality and associated risk factors among middle-aged and older South Africans: findings from the health and ageing in Africa: a longitudinal study of an INDEPTH community in rural South Africa (HAALSI).

    Age and ageing·2026
    Same journal

    Effect of antihypertensive medication reduction on short-term blood pressure control in older adults: calibration of OPTiMISE trial results to real-world primary care data.

    Age and ageing·2026
    Same journal

    New horizons in advance care planning: narratives, identity and cultural humility.

    Age and ageing·2026
    Same journal

    Correction to: How a geriatrician-led emergency department model works in practice: a realist evaluation.

    Age and ageing·2026
    Same journal

    Effects of a home-based exercise and physical activity intervention after inpatient rehabilitation on real-world mobility in older adults with cognitive impairment: a secondary analysis of a randomised controlled trial.

    Age and ageing·2026
    See all related articles

    Area of Science:

    • Endocrinology
    • Exercise Physiology
    • Gerontology

    Background:

    • Aging is associated with metabolic changes and hormonal dysregulation.
    • Exercise is known to influence metabolic health, but its specific effects on hormonal responses in elderly men require further investigation.

    Purpose of the Study:

    • To investigate the impact of regular vigorous exercise on plasma insulin, glucose, and growth hormone levels during oral glucose tolerance tests in elderly men.
    • To explore potential differences in hypothalamic-pituitary regulation between exercising and non-exercising elderly men.

    Main Methods:

    • Oral glucose tolerance test (OGTT) administered to 47 elderly men (exercising vs. control).
    • Plasma insulin and glucose levels measured during OGTT.
    • Growth hormone levels measured during an extended 4-hour OGTT in a subset of participants.

    Related Experiment Videos

    Main Results:

    • Exercising elderly men exhibited significantly lower plasma insulin levels during OGTT compared to controls.
    • No significant differences in plasma glucose or initial growth hormone levels were observed between groups.
    • Control subjects showed a blunted recovery of growth hormone secretion after 4 hours compared to the athletic group.

    Conclusions:

    • Regular vigorous exercise in elderly men is associated with improved insulin sensitivity and enhanced growth hormone secretory dynamics.
    • Differences in hypothalamic control of the pituitary may underlie the observed hormonal variations between exercising and sedentary elderly men.
    • Findings highlight the potential benefits of exercise for maintaining hormonal balance and metabolic health in aging populations.