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The ACVD task force on canine atopic dermatitis (XVII): intradermal testing
1Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, 601 Vernon L. Tharp Street, Columbus, OH 43017, USA. hillier.4@osu.edu
Veterinary Immunology and Immunopathology
|September 13, 2001
Summary
Intradermal testing is a valuable tool for diagnosing IgE-mediated hypersensitivity in both humans and animals. Standardized allergens and clear interpretation criteria would further improve the accuracy of this widely used diagnostic method.
Area of Science:
- Veterinary Medicine
- Immunology
- Dermatology
Background:
- Intradermal testing has a long history of use in human and veterinary medicine.
- Its primary application lies in identifying IgE-mediated allergen hypersensitivity.
- Positive reactions may indicate sub-clinical hypersensitivity, not always overt allergy.
Purpose of the Study:
- To highlight the utility of intradermal testing in allergy diagnosis.
- To emphasize the need for standardization in allergen extracts and result interpretation.
- To underscore its value as a diagnostic tool when conducted properly.
Main Methods:
- Review of established practices in intradermal testing.
- Discussion of diagnostic utility and limitations.
- Consideration of factors for improving test efficacy.
Main Results:
- Intradermal testing effectively demonstrates allergen-specific hypersensitivity.
- Standardization of allergen extracts and interpretation criteria are crucial for enhanced utility.
- The test remains valuable when performed following accepted guidelines.
Conclusions:
- Intradermal testing is a recognized method for diagnosing hypersensitivity.
- Improvements in standardization are recommended to maximize its diagnostic value.
- It is a valuable tool for identifying allergen-specific reactions in clinical practice.