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Severe thrombocytopenia possibly related to readministration of eptifibatide
F L Paradiso-Hardy1, M Madan, S Radhakrishnan
1Department of Pharmacy, Sunnybrook and Women's College Health Sciences Centre, Toronto, Ontario, Canada. fran.paradiso-hardy@swchsc.on.ca
Abstract:
Thrombocytopenia following eptifibatide therapy is a rare event, and acute severe thrombocytopenia following readministration has not been reported. We describe a case of acute severe thrombocytopenia following reexposure to eptifibatide during percutaneous coronary intervention. We continue to monitor platelet counts at 2-4 hr and 16-24 hr following administration of any glycoprotein IIb/IIIa inhibitor. Cathet Cardiovasc Intervent 2001;54:63-67.