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Related Experiment Videos

Artificial saliva substitutes and mineral dissolution.

G Smith1, A J Smith, L Shaw

  • 1School of Dentistry, University of Birmingham, Birmingham, UK.

Journal of Oral Rehabilitation
|September 15, 2001
PubMed
Summary

Most artificial saliva substitutes show minimal tooth erosion potential. However, careful product selection is crucial for patients with reduced salivary flow to protect natural teeth from mineral dissolution.

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Area of Science:

  • Dental science
  • Biomaterials science

Background:

  • Xerostomia (dry mouth) affects numerous individuals, impacting oral health.
  • Artificial saliva substitutes aim to alleviate symptoms and maintain oral functions.
  • The erosive potential of these substitutes on dental tissues is a critical consideration.

Purpose of the Study:

  • To evaluate the erosive effects of commercial artificial saliva substitutes.
  • To assess the in vitro mineral dissolution capabilities of these products.
  • To determine the relationship between pH and erosive potential.

Main Methods:

  • Utilized an in vitro hydroxyapatite powder dissolution assay.
  • Tested a range of commercially available artificial saliva substitutes.
  • Measured mineral dissolution levels to quantify erosive potential.

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Main Results:

  • The majority of tested saliva substitutes exhibited negligible erosive potential.
  • One specific product demonstrated significantly higher mineral dissolution.
  • No clear correlation was observed between the pH of the substitutes and their mineral dissolution levels.

Conclusions:

  • Artificial saliva substitutes can aid patients with impaired salivary flow.
  • Product choice is vital; select substitutes with low erosive potential to safeguard natural dentition.
  • Further research into the formulation of safer saliva substitutes is warranted.