Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Reporter Genes

Reporter Genes

Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
Commonly used reporter...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Mental health impairment and recovery after a road traffic injury: where do we stand in Europe?

Frontiers in public health·2024

Same author

POP culture: the increasing perils of publish or perish. A farewell from the Editors in Chief.

Techniques in coloproctology·2024

Same author

Correction to: The impact of COVID-19 on surgical training: a systematic review.

Techniques in coloproctology·2021

Same author

Age-related changes in muscle architecture and metabolism in humans: The likely contribution of physical inactivity to age-related functional decline.

Ageing research reviews·2021

Same author

The impact of COVID-19 on surgical training: a systematic review.

Techniques in coloproctology·2021

Same author

Systematic review: the effect of right hemicolectomy for cancer on postoperative bowel function.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer·2020

Search research articles

Related Experiment Video

Updated: Jul 11, 2026

Determining Genetic Expression Profiles in C. elegans Using Microarray and Real-time PCR

Determining Genetic Expression Profiles in C. elegans Using Microarray and Real-time PCR

Published on: July 30, 2011

A gene expression map for Caenorhabditis elegans.

S K Kim¹, J Lund, M Kiraly

¹Department of Developmental Biology and Genetics, Stanford University Medical School, Stanford, CA 94305, USA. kim@cmgm.stanford.edu

Science (New York, N.Y.)

|September 15, 2001

Summary

Researchers mapped gene expression in Caenorhabditis elegans using DNA microarrays. This gene expression map aids in discovering co-regulated genes and novel genetic functions, including genomic instability.

More Related Videos

The C. elegans Intestine As a Model for Intercellular Lumen Morphogenesis and In Vivo Polarized Membrane Biogenesis at the Single-cell Level: Labeling by Antibody Staining, RNAi Loss-of-function Analysis and Imaging

The C. elegans Intestine As a Model for Intercellular Lumen Morphogenesis and In Vivo Polarized Membrane Biogenesis at the Single-cell Level: Labeling by Antibody Staining, RNAi Loss-of-function Analysis and Imaging

Published on: October 3, 2017

Hand Dissection of Caenorhabditis elegans Intestines

Hand Dissection of Caenorhabditis elegans Intestines

Published on: September 13, 2022

Related Experiment Videos

Last Updated: Jul 11, 2026

Determining Genetic Expression Profiles in C. elegans Using Microarray and Real-time PCR

Determining Genetic Expression Profiles in C. elegans Using Microarray and Real-time PCR

Published on: July 30, 2011

The C. elegans Intestine As a Model for Intercellular Lumen Morphogenesis and In Vivo Polarized Membrane Biogenesis at the Single-cell Level: Labeling by Antibody Staining, RNAi Loss-of-function Analysis and Imaging

The C. elegans Intestine As a Model for Intercellular Lumen Morphogenesis and In Vivo Polarized Membrane Biogenesis at the Single-cell Level: Labeling by Antibody Staining, RNAi Loss-of-function Analysis and Imaging

Published on: October 3, 2017

Hand Dissection of Caenorhabditis elegans Intestines

Hand Dissection of Caenorhabditis elegans Intestines

Published on: September 13, 2022

Area of Science:

Genomics
Molecular Biology
Developmental Biology

Background:

Understanding gene regulation is crucial for deciphering complex biological processes.
Caenorhabditis elegans is a powerful model organism for genetic studies.

Purpose of the Study:

To develop a novel visualization tool for analyzing large-scale gene expression data.
To identify co-regulated genes and uncover new gene functions using DNA microarray data.

Main Methods:

Assembly of DNA microarray data from diverse Caenorhabditis elegans experiments.
Grouping co-regulated genes based on expression profiles.
Visualization of gene expression correlations and density in a 3D map.

Main Results:

Development of a three-dimensional gene expression map.
Demonstration of the map's utility in identifying co-regulated gene sets (e.g., heat shock, germ line genes).
Uncovering potential novel genetic functions, such as genomic instability in male C. elegans.

Conclusions:

The 3D gene expression map serves as an effective tool for gene discovery.
This approach facilitates the identification of functionally related genes and novel biological insights.
The study highlights the potential of systems-level analysis in uncovering complex genetic phenomena.