Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vascular responses in the equine digit.

N E Robinson, J M Dabney, W J Weidner

    American Journal of Veterinary Research
    |August 1, 1975
    PubMed
    Summary

    The equine digital vasculature does not exhibit autoregulation or reactive hyperemia. It responds to vasoactive agents, similar to canine vasculature, with varying effects from prostaglandins.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Gender equity of authorship in pulmonary medicine over the past decade.

    Pulmonology·2023
    Same author

    Uppermost crustal structure regulates the flow of the Greenland Ice Sheet.

    Nature communications·2021
    Same author

    Review: Perspective on high-performing dairy cows and herds.

    Animal : an international journal of animal bioscience·2021
    Same author

    First Report of a 16SrII-D Subgroup Phytoplasma Associated with Pale Purple Coneflower Witches'-Broom Disease in Australia.

    Plant disease·2019
    Same author

    Invited review: Learning from the future-A vision for dairy farms and cows in 2067.

    Journal of dairy science·2018
    Same author

    Equine asthma: An appropriate, translational and comprehendible terminology?

    Equine veterinary journal·2016

    Area of Science:

    • Veterinary Medicine
    • Cardiovascular Physiology
    • Equine Science

    Background:

    • Understanding the microcirculation of equine limbs is crucial for diagnosing and treating lameness and circulatory disorders.
    • Previous research has primarily focused on larger vessels, leaving the digital circulation's response to flow changes and vasoactive substances less understood.

    Purpose of the Study:

    • To investigate the autoregulation and reactive hyperemia of the equine digital circulation.
    • To determine the effects of various vasoactive agents on the equine digital vasculature.

    Main Methods:

    • Isolation of the digital circulation in 12 ponies under pentobarbital anesthesia.
    • Controlled blood flow using a pump or natural perfusion.
    • Administration of acetylcholine, histamine, prostaglandins (E1, E2, A1, F2alpha), epinephrine, and serotonin.

    Main Results:

    • No evidence of autoregulation or reactive hyperemia was observed in response to rapid blood flow changes or stoppages.
    • Acetylcholine, histamine, and prostaglandins E1/E2 decreased prevenous resistance.
    • Epinephrine and serotonin induced prevenous constriction, with high doses constricting venous caliber.
    • Prostaglandins A1 and F2alpha showed variable effects.

    Conclusions:

    • The equine digital vasculature lacks autoregulation and reactive hyperemia.
    • It exhibits sensitivity to vasoactive agents, similar to the canine forelimb skin vasculature.
    • These findings provide insights into equine circulatory control and potential therapeutic targets.

    Related Experiment Videos