Related Experiment Video
Updated: Aug 14, 2026

The Synthesis, Characterization and Reactivity of a Series of Ruthenium N-triphosPh Complexes
Published on: April 10, 2015
Optically active ortho-metalated half-sandwich ruthenium complexes: solid-state NMR as a convenient tool to analyze
V Ritleng1, P Bertani, M Pfeffer
1Laboratoire de Synthèses Métallo-Induites, UMR CNRS 7513 Université Louis Pasteur, 4 rue Blaise Pascal, 67070 Strasbourg, France.
Abstract:
Bulk solid samples of various ratios of the cyclometalated arene ruthenium diastereomers (S)Ru- and (R)Ru-[(eta(6)-C6H6)Ru(C6H4-2-(R)-CH(Me)NMe2)PMe2Ph](+)PF6(-) (3a/3b), of which the configurational stability at the metal center has been established by classical solution techniques, have been analyzed by the 13C cross-polarization magic angle spinning (CP-MAS) and 31P MAS NMR. The spectra obtained allowed us to detect both isomers and to estimate their respective proportions by 31P spectra. This technique was applied to a bulk solid sample of the diastereomers (S)Ru- and (R)Ru-[(eta(6)-C6H6)Ru(C6H4-2-(R)-CH(Me)NMe2)NCMe](+)PF6(-) (1a/1b), which were shown to be configurationally labile by classical solution experiments. Detection of isomer 1a only in the resulting 13C CP-MAS NMR spectrum demonstrated that there has been epimerization of 1b to 1a during crystallization, thus confirming the configurational lability at the metal center.
Related Concept Videos
Stereoisomerism
Isomers are different chemical species that have the same chemical formula.
Transition metal complexes often exist as geometric isomers, in which the same atoms are connected through the same types of bonds but with differences in their orientation in space. Coordination complexes with two different ligands in the cis and trans positions from a ligand of interest form isomers. For example, the octahedral [Co(NH3)4Cl2]+ ion has two isomers (Figure 1) In the cis...
Stereoisomerism of Cyclic Compounds
¹H NMR: Complex Splitting
Splitting diagrams or splitting tree diagrams are routinely used to depict such complex couplings. While drawing splitting diagrams, the splitting with the larger coupling constant is usually applied first.
¹H NMR of Conformationally Flexible Molecules: Temporal Resolution
¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)
¹H NMR Chemical Shift Equivalence: Enantiotopic and Diastereotopic Protons
In chiral compounds such as 2-butanol, replacing the methylene hydrogens at C3 produces a pair of...

