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Updated: Oct 4, 2026

Transformation of Probiotic Yeast and Their Recovery from Gastrointestinal Immune Tissues Following Oral Gavage in Mice
Published on: February 8, 2016
Utilization of prebiotic carbohydrates by yeasts of therapeutic relevance
G Mitterdorfer1, W Kneifel, H Viernstein
1Department of Dairy Research and Bacteriology, University of Agricultural Sciences, Gregor Mendel-Strasse 33, A-1180 Vienna, Austria.
Aims:
To investigate 17 strains of therapeutically relevant strains of Saccharomyces cerevisiae (including 10 strains of so-called S. boulardii) isolated from various pharmaceutical products, feed supplements and brewer's yeast for their capability of utilizing selected carbohydrates of prebiotic importance.
Methods And Results:
Automated turbidimetric measurements and conventional test combinations were used to examine the basic sugar assimilation profiles of the test strains. It was shown that none of the so-called S. boulardii strains utilized galactose and palatinose. Among the prebiotic substrates, the yeasts indicated a pronounced preference for metabolizing the fructo-oligosaccharides.
Conclusion:
Yeast strains of therapeutic relevance can be successfully combined with certain prebiotics in symbiotic formulations.
Significance And Impact Of The Study:
The results of this study may serve as a basis for the development of new pharmaceutical preparations for medical therapy and a better understanding of intestinal micro-ecology.
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