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[Brugada syndrome].

S Fischer1, S Reinhold, W Kettner

  • 1Kardiologische Abteilung der Medizinischen Klinik, Städtisches Klinikum Magdeburg, Krankenhaus Altstadt. DrFischerS@web.de

Medizinische Klinik (Munich, Germany : 1983)
|September 19, 2001
PubMed
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Brugada syndrome, a heart condition, was unmasked in a patient by prajmalium bitartrate medication. This case highlights the importance of drug-induced Brugada syndrome diagnosis and management with an ICD pacemaker.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Pharmacology

Background:

  • Brugada syndrome is characterized by a specific ECG pattern, including a high take-off descending ST segment with right bundle branch block.
  • This condition predisposes individuals to life-threatening ventricular arrhythmias and syncope, particularly with a family history.

Observation:

  • A 56-year-old male patient presented with symptomatic ventricular extrasystoles.
  • Treatment with oral prajmalium bitartrate unmasked an electrocardiographic pattern consistent with Brugada syndrome.

Findings:

  • The patient's medication revealed a characteristic Brugada syndrome pattern on ECG.
  • Right ventricular dysplasia was considered as a possible co-existing condition following invasive diagnostics.

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Implications:

  • This case underscores the potential for drug-induced Brugada syndrome, emphasizing careful medication review in affected patients.
  • Implantation of an implantable cardioverter-defibrillator (ICD) pacemaker was necessary for managing the patient's cardiac condition.