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Updated: May 5, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Psychiatric morbidity in psoriasis and vitiligo: a comparative study
N Sharma1, R V Koranne, R K Singh
1Department of Dermatology and Venereology, Lady Hardinge Medical College and Associated Hospitals, New Delhi, India.
Psoriasis patients exhibit significantly higher psychiatric morbidity, including depression and sleep disturbances, compared to vitiligo patients. This study highlights the mental health burden associated with psoriasis.
Area of Science:
- Psychiatry
- Dermatology
- Psychosomatic Medicine
Background:
- Psoriasis and vitiligo are chronic skin conditions.
- Psychiatric conditions are common comorbidities in dermatological disorders.
- The General Health Questionnaire (GHQ-H) is a validated tool for assessing psychiatric morbidity.
Purpose of the Study:
- To compare psychiatric morbidity in patients with psoriasis versus vitiligo.
- To assess the prevalence of depression, anxiety, and sleep disturbances in these patient groups.
Main Methods:
- A comparative study involving 30 new, untreated psoriasis patients and 30 vitiligo patients (ages 18-60).
- Utilized the standardized Hindi version of the General Health Questionnaire (GHQ-H) for assessment.
- Statistical analysis to determine significant differences between groups.
Main Results:
- Psychiatric morbidity was significantly higher in psoriasis patients (53.3%) than in vitiligo patients (16.22%) (p=0.0028).
- Depression prevalence was 23.3% in psoriasis and 10% in vitiligo.
- Sleep disturbance was the most frequent complaint, significantly more prevalent in psoriasis patients (56.6%) compared to vitiligo patients (20%) (p=0.0034).
Conclusions:
- Psoriasis is associated with a substantially higher burden of psychiatric morbidity than vitiligo.
- Sleep disturbances are a prominent issue in psoriasis patients.
- These findings underscore the importance of screening for and managing psychiatric comorbidities in psoriasis.
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